Identification and functional annotation of novel microRNAs in the proximal sciatic nerve after sciatic nerve transection
نویسندگان
چکیده
منابع مشابه
Differential Gene Expression Profiling and Biological Process Analysis in Proximal Nerve Segments after Sciatic Nerve Transection
After traumatic injury, peripheral nerves can spontaneously regenerate through highly sophisticated and dynamic processes that are regulated by multiple cellular elements and molecular factors. Despite evidence of morphological changes and of expression changes of a few regulatory genes, global knowledge of gene expression changes and related biological processes during peripheral nerve injury ...
متن کاملSciatic functional index following induction of injury in the sciatic nerve of rats
Sciatic functional index (SFI) as a behavioral method was used to assess the functional recovery following experimentally-induced various injuries in the sciatic nerve, spinal cord, and brain. In the present study, the functional recovery after induction of injury in the sciatic nerve was investigated in rats using SFI. Twenty-four rats were divided into three groups including sham-operated (SS...
متن کاملP187: Dose-Dependent Delay of Wallerian Degeneration Induced by Dexamethasone after Sciatic Nerve Transection in Rat
Wallerian degeneration is an innate immune response which occurs after some kinds of nerve damages such as neurodegenerative disease and acute axonal injury. In clinic, dexamethasone as an anti-inflammatory drug has been used for many years to treat nerve injuries. In present study, we aimed to study the effects of various doses of dexamethasone on the Wallerian degeneration in rat. Twentyseven ...
متن کاملSciatic functional index following induction of injury in the sciatic nerve of rats
Sciatic functional index (SFI) as a behavioral method was used to assess the functional recovery following experimentally-induced various injuries in the sciatic nerve, spinal cord, and brain. In the present study, the functional recovery after induction of injury in the sciatic nerve was investigated in rats using SFI. Twenty-four rats were divided into three groups including sham-operated (SS...
متن کاملMorphological changes of lumbar spinal neurons after sciatic nerve transection in neonate rats
Axotomy of the sciatic nerve have been documented to cause neuronal loss, especially in newborn rats. Few works have focused on time course of neuronal loss and the type of cell death, which occurs after axotomy. Forty rat pups were anesthetized by hypothermia and the right sciatic nerve transected at five days of their age and the left side was used as control. The operated animals were sacrif...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science China Life Sciences
سال: 2011
ISSN: 1674-7305,1869-1889
DOI: 10.1007/s11427-011-4213-7